26 Kasım 2011 Cumartesi

SICKLE CELL ANEMIA

The Oxygen binding proteins have disorders sometimes and that causes serious genetic diseases as sickle cell anemia. Sickle cell disease is a serious genetic disorder that the body produces sickle-shaped red blood cells. “Sickle-shaped” means that the red blood cells are shaped as a crescent. Sickled cells are fragile and they can rupture easily. Thus, it makes the lack of blood that is called as “anemia”. To explain briefly, anemia is a condition in which your blood has a lower than normal number of red blood cells. It can kill the people because the capillaries become blocked by the sickle shaped of the cells. Thus, the people who have the sickle cell anemia can be killed by the blokage. This blokage can interfere the function of organs.
Sickle cell anemia is a genetic disorder and it can not be treated. Generally, people die at their childhood because of sickle celled anemia. In addition to these, sickle cell trait is not as anemia because the people who have sickle cell trait do not have disease. It occurs because of one allel. These kind of people have one normal allel and other allel has the trait. This trait can be inherited from father or mother.
With the blood tests it can be determined that people have the disease or do not have the disease. Generally, sickled cell anemia and sickle cell trait can be seen in the Africa. It makes the people tired and people have pain. It needs care for living with this trait. In addition to this, it can be passed through the parents to the children. Thus, making test before having the baby can eliminate the risk of having the disease. Early diagnosing the diseases preferably in the newnborn period. Blood transfusions help benefit sickle cell disease patients with reducing pains and other complications. Thus, red blood cells contain iron, and there is no way to get off it from the body of patients who have blood transfusions can accumulate iron in the body until it reaches toxic levels. It is important to remove excess iron from the body, because it can damage the organs.
RESOURCES
  • Nelson D. and Cox M., Principles of Biochemistry, 5th edition, Lehninger
  • What Is Sickle Cell Anemia?, Retrieved from

  • What Is Sickle Cell Anemia?, Retrieved from

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